Light-activated Nanoparticle for Uveal Melanoma

https://www.aao.org/interview/light-activated-nanoparticle-therapy-uveal-melanom   In this interview from AAO 2019, Dr. Carol Shields discusses a new light-activated nanoparticle therapy (AU-011) for ocular melanoma. The particle, which is attached to a chromophore, binds to melanoma cells and is activated by a 689-nanometer light. Early-stage trials look promising, she explains, with preliminary results demonstrating minimal vision loss, suggesting this […]

Malignant Transformation

https://www.aao.org/1-minute-video/multimodal-imaging-signs-of-malignant-transformati In this 1-Minute Video, Dr. Carol Shields offers tips for managing patients who present with a pigmented lesion at the back of the eye. Risk factors that predict the transformation of choroidal nevus in melanoma can be remembered with the following mnemonic: To Find Small Ocular Melanoma Doing IMaging. T: thickness over two millimeters; […]

Treating Iris Melanoma

In this 1-Minute video, Dr. Carol Shields offers advice for treating iris melanoma. Ocular oncologists generally devise treatment strategies based on tumor size, location and shedding of pigment. Small tumors are typically resected, while large tumors might be treated with radiotherapy. But enucleation may be necessary for tumors that have shed pigment. Tube shunts and […]

Differentiating Benign vs Malignant Conjunctival Tumors in Children

“There have been only a few series on conjunctival tumors in children, most of which have been histopathologic series and only one substantial previous clinical series on 262 cases from our department. In this current analysis, we assessed a large cohort of 806 consecutive conjunctiva tumors in children, and assessed, for the first time in […]

Building A Practice And A Relationship

Click to continue reading this wonderful article written about Drs. Carol & Jerry Shields; Soon to be found in EyeWorld Magazine’s February 2017 edition.